A DNA template having the base sequence A-G-A-T-G-A would produce a mRNA with a base sequence of ______.
A) A-G-A-T-G-A
B) U-C-U-A-C-U
D) T-C-T-U-C-T
E) T-C-T-A-C-A
F) A-C-A-U-C-*
G) T-C-T-G-C-T
To determine the base sequence of the mRNA produced from a given DNA template, you need to follow the complementary base pairing rules. In DNA, adenine (A) always pairs with thymine (T), and guanine (G) always pairs with cytosine (C). However, in mRNA, thymine (T) is replaced by uracil (U).
Given that the DNA template has the base sequence A-G-A-T-G-A, the complementary bases in mRNA would be:
T-C-T-A-C-T
So, the correct answer is E) T-C-T-A-C-A
To transcribe DNA into mRNA, the following base pairing rules should be followed:
- Adenine (A) in DNA pairs with Uracil (U) in RNA.
- Thymine (T) in DNA pairs with Adenine (A) in RNA.
- Guanine (G) in DNA pairs with Cytosine (C) in RNA.
- Cytosine (C) in DNA pairs with Guanine (G) in RNA.
Given the DNA template sequence 'A-G-A-T-G-A', we can transcribe it step-by-step:
1. Adenine (A) pairs with Uracil (U): A → U.
2. Guanine (G) pairs with Cytosine (C): G → C.
3. Adenine (A) pairs with Uracil (U): A → U.
4. Thymine (T) pairs with Adenine (A): T → A.
5. Guanine (G) pairs with Cytosine (C): G → C.
6. Adenine (A) pairs with Uracil (U): A → U.
Therefore, the mRNA base sequence produced from the given DNA template sequence 'A-G-A-T-G-A' is U-C-U-A-C-U.
So, the correct answer is B) U-C-U-A-C-U.