'In' means 'no longer than a particular period of time' or 'at the end of a particular period of time.'

1. Can you finish the job in two weeks?
1-2. Can you finish the job in less than two weeks?
(Are both the same?)

2. I should be there in half an hour.
2-2. I should be there at the end of half an hour.
(Are both the same?)

3. I will leave for London ____ two days.
(If I may leave for London two days later, three days later, a week later, two weeks later, etc., what prepositions should we use in this blank?)

1 and 1-2 are almost the same.

2 and 2-2 are the same.

In 3, I'd use "in."

1. In the context of time, "in" indicates that something will be completed within a specific period or by the end of that period. Therefore, both sentences have a similar meaning but express different levels of urgency or time constraint.

- "Can you finish the job in two weeks?" suggests that the job should be completed within exactly two weeks.
- "Can you finish the job in less than two weeks?" implies that finishing the job within a time frame shorter than two weeks would also be acceptable.

2. Similarly, in the context of time, "in" can also indicate that something will happen within or by the end of a specific time period. In these sentences, the meanings are similar but the phrasing differs slightly.

- "I should be there in half an hour" means that you will arrive at the location within the next thirty minutes.
- "I should be there at the end of half an hour" implies that you will arrive precisely at the thirtieth-minute mark.

3. To correctly fill in the blank in the sentence "I will leave for London ____ two days," different prepositions can be used depending on the intended meaning.

- "I will leave for London after two days" implies that you will depart two days from now.
- "I will leave for London in two days" means that you plan to depart precisely two days from now.
- "I will leave for London within two days" expresses that you will leave anytime within the next two days.

The choice of preposition depends on whether you want to indicate an exact period of two days, leaving immediately after two days, or leaving within that two-day timeframe.