Can a genotype be a lowercase letter than a uppercase letter? if not, why not?

No, a genotype cannot consist of both a lowercase letter and an uppercase letter. The reason is that genotypes are typically represented using uppercase letters to denote dominant traits and lowercase letters to denote recessive traits.

In genetics, genotypes represent the inherited combination of alleles for a particular gene. Alleles are the alternate forms of a gene that can exist at a specific location on a chromosome. Uppercase letters are commonly used to represent dominant alleles, which are expressed in an individual's physical traits regardless of the presence of any other allele. Lowercase letters, on the other hand, are used to represent recessive alleles, which are only expressed when there are no dominant alleles present.

For example, let's consider a trait like eye color. The allele for brown eye color is generally dominant (B), while the allele for blue eye color is recessive (b). If an individual has one or two copies of the dominant allele (BB or Bb), they will have brown eyes because the dominant allele overrides the recessive allele. However, if an individual has two copies of the recessive allele (bb), they will have blue eyes because there are no dominant alleles to override the expression of the recessive allele.

Therefore, genotypes are typically represented using either uppercase letters (for dominant alleles) or lowercase letters (for recessive alleles), but not a combination of both in the same gene locus.