Can you put this sentence into completely every word in present tense and still make this sentence make sense.

Humans are never satisfied

I don't understand. What are you asking?

To put this sentence into every word in present tense and still make it make sense, you would change the verb "are" to "are" to maintain the subject-verb agreement in present tense. Since the adverb "never" does not require any changes, the sentence would become:

Humans are never satisfiable.