A water jet approximately 10ft in length & 6-7 inches in diameter traveling @ mach3.5-4.5 hitting an object traveling @ mach 5, 10-15ft in length with a weight of 2500 lbs can its course of travel be altered, and/or can said object be destroyed completely?

I'd say either. If the object is a turkey, chances are it'll be obliterated.

If it's a flying block of titanium, it's more likely to have its course altered.