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November 27, 2014

November 27, 2014

Posted by **thane** on Tuesday, July 16, 2013 at 2:38am.

case control

High-fat diet 10 5

Low-fat diet 40 55

50 60

Statistical inferences for odds ratios are based on the natural log of the odds ratio, rather than the odds ratio itself (because the distribution for an odds ratio does not follow a normal distribution). The sampling distribution of the natural log of the odds ratio (lnOR) follows a normal distribution, with standard error

=1a+1b+1c+1d−−−−−−−−−−−−−√

(where a, b, c, and d are the cells in the 2x2 table).

Calculate the odds ratio for breast cancer (comparing high-fat diet to low-fat diet) from the 2x2 table above.

Take the natural log of the odds ratio that you calculated

Calculate the standard error of the lnOR, according to the formula given above.

Calculate the 95% confidence interval for the lnOR.

Convert the upper and lower confidence limits that you calculated in (e) back to odds ratios by exponentiating (i.e., calculate the 95% confidence interval for the OR).

- stats -
**Jeff**, Tuesday, July 16, 2013 at 2:06pmCheating is not allowed. HRP258

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