Posted by **netspirit** on Tuesday, January 15, 2013 at 3:16pm.

Prospective Cohort Study

The following tables show the crude and sex-specific results from a Prospective Cohort Study that examines the association between a binary exposure (E) and the development of a disease (D) during 20 years of follow-up.

Use these data to solve the above problem, it will become easier

Full data

D+ D- Total

E+ 30 270 300

E- 20 180 200

Total 50 450 500

Male

D+ D- Total

E+ 12 108 120

E- 8 72 80

Total 20 180 200

Female

D+ D- Total

E+ 18 162 180

E- 12 108 120

Total 30 270 300

1. Assume that this cohort is a simple random sample from a broader population of interest. Model the number of disease positive individuals among all exposed individuals in the sample using the binomial distribution with probability of disease ; and model the number of disease positive individuals among the unexposed in the sample using a binomial distribution, with probability of disease . Estimate , the proportion of exposed individuals who are disease positive, and provide an exact 95% confidence interval.

Estimated Proportion: ????

Confidence Interval:

Lower Bound:????

Upper Bound:????

and

4. Now, we examine the risk difference between the exposed and unexposed populations. Estimate the risk

difference for the disease and construct a corresponding large-sample 95% confidence interval. Calculate the

risk difference as the proportion of diseased individuals in the exposed minus the proportion of diseased

individuals in the unexposed.

Risk Difference: ????

Confidence Interval:

Lower Bound: ????

Upper Bound: ????

Please help me count this two question, or explain.I need your help!

- Statistics -
**ss**, Tuesday, January 15, 2013 at 11:43pm
Cheating? For a free course where the certificate means nothing? LOL

- Statistics -
**seriously**, Tuesday, January 15, 2013 at 11:52pm
You do realise that the questions are student specific? I've copied your table, for future reference.

- Statistics -
**Anonymous**, Wednesday, January 16, 2013 at 3:50am
Honour code...

- Statistics -
**reply to ss**, Thursday, January 17, 2013 at 4:26am
Course does not study, its you who do it. Therefore course may be free or very expensive, but the gaining knowledge out of it is totally upto you.

- Statistics -
**Anonymous**, Sunday, January 20, 2013 at 4:11am
please suggest the steps for solving this question. requesting you

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