Posted by Amy on Friday, June 8, 2012 at 2:11am.
You provide the manufacturer’s recommended dose of an antibiotic, which is 10mg/kg IV for a 100kg patient. You then draw a level 30 minutes after the dose. Assume rapid distribution and neglible clearance/metabolism over the 30minute period between the time of administration and drug level assement.
3. The serum level of this antibiotic returns at 83.3mg/L. What is the volume of distribution of the drug?
A. 1.6 Liters
B. 16 Liters
C. 12 Liters
D. 1.2 Liters
E. 8 Liters
4. Assume the goal therapeutic serum level of a is 120 mg/L. How much more drug do you need to order to attain this level.
C. 45 mg
5. A patient with chronic kidney disease has a vancomycin serum level drawn that returns at 37mcg/mL. She will require a redose when the level reaches 15mcg/mL. Her half-life has been determined to be 46 hours. How many hours after the initial serum draw will she require a redose.
A. 52 hours
B. 60 hours
C. 67 hours
D. 73 hours
E. 80 hours
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