Posted by John on Monday, June 4, 2012 at 11:39am.
1) In 1951, an African-American woman was admitted to Johns Hopkins Hospital in Baltimore.
2) In those years, scientists had been unsuccessfully trying to grow malignant human cells outside the body to determine what caused cancer and ultimately how to cure it.
3) OK
4) During her first two-night stay in the hospital, doctors sliced several pieces of tissue from her cancerous tumor and placed them in a dish, in hopes of growing and studying them.
4)Neither Lacks nor her family gave permission for her cells to be taken. Most cells, however, died quickly in the lab, and the few that did survive failed to grow. Her cancer cells, however, grew, doubling in number every 24 hours.
5) The doctors realized that these cells -- named HeLa to avoid using Lacks’s name -- had an altered set of chromosomes. In particular, they possessed more than eighty chromosomes for the presence of an abnormal number of pairs of chromosomes 12, 6, 8, and 17.
6) This cell line was peculiar because the papillomavirus, the pathogen responsible for the majority of cervical cancers, induced a mutation in the gene encoding the telomerase, the enzyme responsible for telomere elongation.
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