Wednesday

April 16, 2014

April 16, 2014

Posted by **Katie** on Tuesday, November 15, 2011 at 11:04pm.

Myosin heads bind to active sites on actin molecules

ATP is hydrolyzed

Myosin heads return to their high-energy shape(******), ready for the next working stroke

Calcium ions bind to troponin

Cycling continues until calcium ions are sequestered by the SR

Myosin cross bridges detach from actin

Troponin changes shape

ADP & Pi(inorganic phosphate) are released from the thick filament

Myosin heads pull on the thin filaments(working stroke) & slide them toward the center of sarcomere

ATP binds to thick filament

Tropomyosin is moved into the groove between the F-actin strands exposing active sites on actin

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