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March 27, 2017

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Could you use NaOH to separate acetylsalicylic acid (aspirin) and acetaminophen (Tylenol) by acid-base extraction?

  • organic chemistry - ,

    I don't think so. I think NaOH will react with both a phenol and a carboxylic acid. I think the separation you are looking for can be done with NaHCO3.

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