what are mediators cells
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Mediator cells refer to a type of immune cells called mast cells. Mast cells are granulated cells that play a critical role in the immune response and allergic reactions. They are primarily found in connective tissue, such as the skin, respiratory tract, and gastrointestinal tract.
Mast cells are involved in the mediation of inflammation and allergic responses by releasing various chemical mediators, which include histamine, cytokines, leukotrienes, and prostaglandins. These mediators can trigger blood vessel dilation, attract other immune cells to the site of inflammation, and cause smooth muscle contraction.
Furthermore, mast cells are also involved in host defense against parasites by releasing chemicals that can kill or immobilize them. They express receptors for both IgE antibodies and various other immunoglobulins, which play a role in initiating activation and degranulation of mast cells.
Overall, mediator cells, or mast cells, are an essential part of the immune system and are involved in various immune responses and allergic reactions.