ROH + TsCl + pyridine ----> R-OTs + Cl:
For the reaction, what is the function of pyridine?
The pyridine is on top of the arrow in the question.
a)Serves as a lewis base, stabilizes transition state.
b)Serves as a cofactor,complexes with the alcohol.
c)Weak base. Proton acceptor for hydroxyl.
d)Catalyst, bonds to Tosyl to increase reactivity.
e) Provides comedic relief for the reaction, making sure the chemists aren't too serious about their work! 😄 But in all seriousness, the correct answer is a) Serves as a Lewis base, stabilizes transition state. Pyridine is often used as a base in organic reactions to assist in deprotonation or to act as a nucleophile. It can stabilize the transition state by accepting a proton or donating electrons. Happy chemistry-ing!
Based on the given reaction, the function of pyridine is to serve as a catalyst and bond with Tosyl (Ts) to increase reactivity. Therefore, the correct answer is d) Catalyst, bonds to Tosyl to increase reactivity.
In the given reaction, pyridine is written on top of the arrow, indicating its function in the reaction. To determine the function of pyridine, we can analyze its role based on its properties and its interaction with the other reagents.
Pyridine is a nitrogen-containing aromatic compound. It is commonly used as a solvent in organic reactions and also serves as a catalyst or a base in certain reactions. Let's assess the given options:
a) Serves as a Lewis base, stabilizes the transition state: Pyridine can act as a Lewis base by donating an electron pair from its nitrogen atom. This interaction can help stabilize the transition state during the reaction. Therefore, option (a) could be a possible function of pyridine in this reaction.
b) Serves as a cofactor, complexes with the alcohol: Based on the given reaction, there is no mention of pyridine acting as a cofactor or forming a complex with the alcohol. Hence, option (b) is not a likely function of pyridine.
c) Weak base. Proton acceptor for hydroxyl: Pyridine is a weak base due to the presence of its lone pair of electrons on the nitrogen atom. However, in the given reaction, there is no hydroxyl group present. Therefore, option (c) is not applicable in this case.
d) Catalyst, bonds to Tosyl to increase reactivity: Pyridine can act as a catalyst by forming a complex with certain reagents, as it has the ability to coordinate with various substrates. In this case, pyridine could potentially bond to the tosyl (OTs) group, increasing its reactivity. Hence, option (d) could be a valid function of pyridine in this reaction.
To summarize, based on the given information, the most likely function of pyridine in the reaction is:
d) Catalyst, bonds to Tosyl to increase reactivity.