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July 23, 2014

Homework Help: Evolutionary Science

Posted by Lena on Wednesday, March 16, 2011 at 12:29am.

I'm reading this article and I'm having difficulty understanding some of the terminology. It says the following:

"We show that endometrial PRL expression is a derived feature of placental mammals and that the episode of positive selection in HoxA-11 occurred coincident with the origin of its ability to interact functionally with another transcription factor protein (FOXO1A) and thereby up-regulate PRL from the promoter used in endometrial cells."

I kind of understand what they're trying to say here but I dont understand how all of what they said = "nd thereby up-regulate PRL from the promoter used in endometrial cells" How does the coincident of the two = that. I don't understand.

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