Most folks complain about macro things,the symptoms.
Most researchers will worry about the micro, the virus, bacteria, the pathway.
Most MD's operate in the middle, relieve the symptoms, and fix the problem if possible.
Now for a patient: which is most important? When I have a backache, I think macro, I am not interested in which muscle. I just want (pain) relief. I suspect most folks are macro thinkers. God will cure us in time, if we can just manage our lives as he does it.