Will O2 passively diffuse and bind with hemoglobin that is less than 1mm from the surface of a blood sample?
The percent of hemoglobin bound with O2 is different at high (10% CO2) and low (5% CO2) CO2 concentrations when the Po2 equals 0mmHg. Is that true?
To determine whether O2 will passively diffuse and bind with hemoglobin that is less than 1mm from the surface of a blood sample, we need to consider a few factors.
First, we need to understand that the diffusion of O2 is driven by the concentration gradient between the O2 in the air or solution and the O2 in the blood. If there is a higher concentration of O2 in the air or solution surrounding the blood sample, O2 will tend to diffuse into the blood.
Secondly, the rate of diffusion is influenced by factors such as the partial pressure of O2 (Po2), temperature, surface area, and distance to be traversed. In this case, we are specifically concerned with the distance between the surface of the blood sample and the location where O2 diffusion is to occur.
If the distance between the surface of the blood sample and the location where O2 diffusion is to occur is less than 1mm, it is highly likely that O2 will passively diffuse and bind with hemoglobin. This is because the distance is relatively short, and diffusion can easily occur over such short distances.
Now, let's address the second part of your question regarding the percent of hemoglobin bound with O2 under different CO2 concentrations when the Po2 equals 0mmHg.
The binding of O2 to hemoglobin is influenced by several factors, including the partial pressures of O2 and CO2. When the Po2 is 0mmHg (extremely low), it means that there is no oxygen available in the surrounding environment. In this case, the binding of O2 to hemoglobin depends on other factors, such as the CO2 concentration.
At high CO2 concentrations (e.g., 10% CO2), the Bohr effect comes into play. The Bohr effect states that increased CO2 levels will shift the oxygen-hemoglobin dissociation curve to the right, resulting in decreased hemoglobin affinity for O2. This means that at high CO2 concentrations, less O2 will bind to hemoglobin for a given Po2.
On the other hand, at low CO2 concentrations (e.g., 5% CO2), the oxygen-hemoglobin dissociation curve shifts to the left. This shift indicates an increased affinity of hemoglobin for O2, meaning that more O2 will bind to hemoglobin at the same Po2.
In summary, when the Po2 equals 0mmHg, the percent of hemoglobin bound with O2 is influenced by the CO2 concentration. High CO2 concentrations result in decreased hemoglobin affinity for O2, while low CO2 concentrations lead to increased hemoglobin affinity for O2.