I am reading a book called Angels and Demons by Dan Brown and in the book they talk a lot about antimatter. Does this exist or is it just fictional? If it does exist, is it really a weapon of mass destruction? They say in the book only 1 gram of antimatter can devastate about a half of a mile radius.

Since this is not my area of expertise, I searched Google under the key words "antimatter" to get this:

http://www.google.com/search?client=safari&rls=en&q=antimatter&ie=UTF-8&oe=UTF-8

In the future, you can find the information you desire more quickly, if you use appropriate key words to do your own search. Also see http://hanlib.sou.edu/searchtools/.