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August 20, 2014

Homework Help: Biochemistry

Posted by Sean on Monday, December 7, 2009 at 3:36pm.

A cell has a resting membrane potential of -66 mV and a membrane Cl ion equilibrium potential of -24.0 mV

If a neurotransmitter acts on the cell membrane to open channels that are specifically permeable to Cl, will the membrane potential of the cells change? In which direction?

I'm not sure:

This could mean that the Cl ion permeability is increasing. If so, by the Goldman equation, the overall membrane potential will move towards the Cl ion equilibrium potential. The membrane potential would become less negative.

Or this could mean that the Cl ion becomes unregulated. If so, then Cl would be removed from the Goldman equation and the membrane potential would move away from the Cl ion equilibrium potential. The membrane potential would become more negative.

Please help. Thanks!

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