posted by Ellan .
How did human history in North America during the period described in the Prologue differ from the events of Asia, Eurasia, and Europe? Be specific.
How were these differences important to the international state of affairs in 1450?
Since we don't know what was described in the "Prologue," we can't answer these questions.
North America was unknown to people in Eurasia in 1450 so it had no effect on those people.