(5x^3+2xy6^4+6xy)

It seems like you have provided an expression: (5x^3 + 2xy6^4 + 6xy). However, there seems to be a typographical error in the expression. The term "xy6^4" seems to be incorrect.

To simplify expressions like the one you've provided, we can combine like terms, which means grouping together similar terms.

Let's simplify the given expression step-by-step:

1. Combine the like terms with the same variables:
5x^3 + (2xy6^4) + 6xy

2. Simplify the exponent:
5x^3 + (2xy * 6^4) + 6xy

Note: 6^4 means 6 raised to the power of 4, which is 6 * 6 * 6 * 6 = 1296.

3. Continue simplifying:
5x^3 + 2xy * 1296 + 6xy

4. Multiply the coefficients and simplify further:
5x^3 + 2592xy + 6xy

5. Combine the like terms:
Final simplified expression: 5x^3 + 2598xy.

Therefore, the simplified expression for (5x^3+2xy6^4+6xy) is 5x^3 + 2598xy.