posted by peter on .
How does sickle cell anemia occur--what type of mmutation is it--is it a substitution, deletion, or insertion mutation--or is it all three?
Also, How would gene splicing, cloning, or stem cells help a patient with sickle cell---would any of these be any help at all..how???
sickle cell anemia is an autosomal recessive trait. it is caused by the production of an abnormal type of hemoglobin. the proteins of the hemoglobin stick together, making the red blood cell rigid and form into a sickle shape. its a mutation of a single nucleotide, which i think would be considered a substitution.
ok thank you that makes sense.....but do you know how gene splicing, cloning or stem cells would help a patient