Calculate the average daily dose (ADD) for each route of exposure.

Parameter Average Units Distribution
TCE concentration in water 225 ug/L Uniform
183 - 267 ug/L
Water intake 0.87 L/day Normal
Mean: 0.87 L/day
95th percentile: 2 L/day
TCE concentration in ambient air 0.86 ug/m3 Uniform
0.51 - 1.22 ug/m3
Breathing rate 13.1 m3/day Normal
Mean: 13.1 m3/day
95th percentile: 19.3 m3/day
TCE concentration in room during a shower 1033 ug/m3 Uniform
689 - 1378 ug/m3
Time per shower 10 minutes Normal
Mean: 10 minutes
Std dev.: 5 minutes
Body Weight 52 kg Normal
Mean: 52 kg
Std dev.: 10 kg
Exposure duration 10 years
Average lifetime 70 years
Cancer potency for inhalation 5.88E-6 kg-day/ug
Cancer potency for ingestion 1.1E-4 kg-day/ug

0.991

To calculate the Average Daily Dose (ADD) for each route of exposure, we need to consider the relevant parameters and their distributions.

For each route of exposure, we'll use the formula: ADD = concentration * intake * duration * conversion factor

1. TCE exposure through water ingestion:
- TCE concentration in water: The average concentration is given as 225 ug/L, with a uniform distribution of 183-267 ug/L.
- Water intake: The average water intake is given as 0.87 L/day, following a normal distribution with a mean of 0.87 L/day and a 95th percentile of 2 L/day.
- Duration: The exposure duration is mentioned as 10 years.
- Conversion factor: The cancer potency for ingestion is given as 1.1E-4 kg-day/ug.

Using these parameters, we can calculate the ADD for TCE exposure through water ingestion as follows:
- Calculate the average concentration within the given range: (183 + 267) / 2 = 225 ug/L
- Calculate the ADD: ADD = (225 ug/L) * (0.87 L/day) * (10 years) * (1.1E-4 kg-day/ug)

2. TCE exposure through ambient air inhalation:
- TCE concentration in ambient air: The average concentration is given as 0.86 ug/m3, with a uniform distribution of 0.51-1.22 ug/m3.
- Breathing rate: The average breathing rate is given as 13.1 m3/day, following a normal distribution with a mean of 13.1 m3/day and a 95th percentile of 19.3 m3/day.
- Duration: The exposure duration is mentioned as 10 years.
- Conversion factor: The cancer potency for inhalation is given as 5.88E-6 kg-day/ug.

Using these parameters, we can calculate the ADD for TCE exposure through ambient air inhalation as follows:
- Calculate the average concentration within the given range: (0.51 + 1.22) / 2 = 0.86 ug/m3
- Calculate the ADD: ADD = (0.86 ug/m3) * (13.1 m3/day) * (10 years) * (5.88E-6 kg-day/ug)

3. TCE exposure through room air during a shower:
- TCE concentration in room during a shower: The average concentration is given as 1033 ug/m3, with a uniform distribution of 689-1378 ug/m3.
- Time per shower: The average time per shower is given as 10 minutes, following a normal distribution with a mean of 10 minutes and a standard deviation of 5 minutes.
- Duration: The exposure duration is mentioned as 10 years.
- Conversion factor: The cancer potency for inhalation is given as 5.88E-6 kg-day/ug.

Using these parameters, we can calculate the ADD for TCE exposure through room air during a shower as follows:
- Calculate the average concentration within the given range: (689 + 1378) / 2 = 1033 ug/m3
- Calculate the ADD: ADD = (1033 ug/m3) * (duration of showers per day) * (10 years) * (5.88E-6 kg-day/ug)

Note: The body weight and average lifetime parameters are not used in the calculation of ADD but may be relevant in assessing the health risks associated with the exposure.