Ionophores are drugs that act as channels in membranes. Each ionophore has its own specificity with regard to the type of ion that will pass through it. The selected ion is able to move across the membrane in either direction, depending only upon the prevailing concentration gradient.
A certain drug, carbonyl cyanide hydrazone, acts as a proton ionophore and gets inserted into the membranes of pre-lysosomal vesicles as they bud off of the Golgi apparatus. What effect would this ionophore have on the formation of lysosomal vesicles and the activity of the contents?