Can some one help me I don’t know what to take out from the aspirin molecule, for the following structures?
I have to generate a copy of the molecular structure of aspirin and then for each of the molecular features listed in (i) – (iii) have to produce a related structure which, if synthesised and tested, would show the importance of the molecular feature of the aspirin molecule, in its action of relieving pain.
(i)the carboxylic acid group
(ii)the size of the hydrocarbon group on the ester.
(iii)the distance between the oxygen atom joined to the ring and the –OH group of the carboxylic acid.
Have to write a brief explanation of how each of the structures enables the importance of the molecular feature to be determined. No more then 50 words for each case. I have to change only one feature of the aspirin molecule at a time to produce each of the three compounds to be tested and to make sure that the valencies of all the atoms are correct in the new structures.
Science help needed here.
And I have already answered this..
To determine the importance of different molecular features of aspirin in its pain-relieving action, you need to modify the structure of aspirin accordingly. Here's how you can do it:
(i) To determine the importance of the carboxylic acid group, you can remove or modify this group in the aspirin molecule. For example, you can replace the carboxylic acid group with a different functional group, such as a hydroxyl group. By synthesizing and testing this modified structure, you can assess the impact of the carboxylic acid group on the pain-relieving action.
(ii) To determine the importance of the size of the hydrocarbon group on the ester, you can alter the length or structure of the hydrocarbon chain attached to the ester part of the aspirin molecule. For instance, you can increase or decrease the carbon chain length. By synthesizing and testing these modified structures, you can evaluate the influence of the hydrocarbon group size on the pain-relieving action.
(iii) To determine the importance of the distance between the oxygen atom joined to the ring and the -OH group of the carboxylic acid, you can modify the position or length of the connecting chain between these two groups. By altering the carbon chain length or introducing a different linkage, you can create a modified structure. Testing this modified structure will help you understand the significance of the distance between these two groups in the aspirin molecule's pain-relieving action.
Remember to ensure that the valencies of all atoms are correct in the new structures you create. By synthesizing and testing these modifications, you can assess the impact of each molecular feature on the pain-relieving mechanism of aspirin.