Wednesday
September 17, 2014

Homework Help: Chemistry

Posted by Bean on Wednesday, March 14, 2007 at 4:44pm.

Identify 2 examples of the atoms or groups in the compound tocainide that could be involved in its binding to receptor sites in the body via hydrogen bonding. Give reasons for your conclusions. I have gathered that OH- and NH- bonds are an option, is this correct and if so why are these good? Thanks

Here is the structural formula for tocainide. I don't see an OH group. There an amine group (-NH2) and a secondary amide(Ar-NHOC-R). I don't know anything about binding sites. According to some Internet sites tocainide is sometimes sold as the hydrochloride (meaning that HCl has been added to the amine group to form the salt). http://lysine.pharm.utah.edu/netpharm/netpharm_00/gifs/tocainide.gif

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