Is this sentence correct?

The creature sat upright and tugged at the shackles binding his ankles; Frankenstein uttered a piercing scream.

Yes, it's fine.

To determine if a sentence is correct, we need to analyze its grammar and use of punctuation. Let's break down the sentence:

1. "The creature sat upright and tugged at the shackles binding his ankles" - This portion of the sentence is grammatically correct. It describes the actions of the creature.

2. "; Frankenstein uttered a piercing scream" - The use of a semicolon (;) followed by "Frankenstein uttered a piercing scream" is also correct. The semicolon is used to connect two related independent clauses.

Overall, the sentence is grammatically correct and properly punctuated.