Think on two complex tinkertoy models that exactly fit one way only. Compare that to the substrate (one tinkertoy model) and the enzyme (the other model).
In fact, the lock and key model fits several chemical, biological, and cellular reactions.
(Broken Link Removed)
http://en.wikipedia.org/wiki/Enzyme
Can someone plz help me with this.
I don't know how to explain the lock-and-key model of enzyme function.
Since info can be added, edited by anyone in Wikipedia, I am not sure whether to trust that the info in wikipedia is correct. What do you think Dr. Pursley??
I personally have had very little problem with Wiki. Independent studies have confirmed the error rate is less than Britticana.
In controversial areas frought with opinion, Wiki is about as good as other references...everyone having an ax to grind.
I generally trust Wiki, but do look at other sources. Wiki is quick, easy, and generally reliable.
You made a good point.
The lock-and-key model is an analogy used to describe how enzymes work in chemical reactions. Enzymes are proteins that act as biological catalysts, speeding up chemical reactions in our bodies without being consumed in the process.
In the lock-and-key model, the substrate (one tinkertoy model) represents the molecule upon which the enzyme acts. The enzyme itself (the other tinkertoy model) is specifically shaped to fit the substrate, just like a key fits into a lock. This specific matching of shapes allows the enzyme to bind with the substrate, forming an enzyme-substrate complex.
Once the enzyme and substrate are bound together, the enzyme can then facilitate the chemical reaction by lowering the activation energy required for the reaction to occur. This means that the enzyme helps the reaction proceed more quickly and with less energy input.
The lock-and-key model explains why enzymes are highly specific in their actions. Just like a key can only fit into a specific lock, an enzyme can only bind with a specific substrate that matches its shape. This specificity ensures that enzymes only catalyze the correct reactions and do not interfere with other molecules in the body.
Regarding your concerns about relying on Wikipedia, it's good to approach any source of information critically. While Wikipedia can be a useful starting point, it's always a good idea to cross-reference the information with reliable sources and scientific literature to verify its accuracy. As you mentioned, independent studies have shown that the error rate in Wikipedia is relatively low, and it can be a good resource for general knowledge. However, for more in-depth and accurate information, it's always best to consult peer-reviewed journals and textbooks in the field.