For membrane-associated proteins, the consensus sequence _______ is found on the inchoate (new) polypeptide and ______ to halt.
a. pribnow, replication
b. signal peptidase, transcription
c. stop-transfer peptide, transcription
d. stop-transfer sequence, translation
e. stop-transfer sequence, translation
I thing the answer is "e". please check.
To determine the correct answer, let's analyze each option:
a. Pribnow sequence is a consensus sequence found in DNA that is involved in binding the RNA polymerase during transcription initiation. It is not related to membrane-associated proteins or halting of translation.
b. Signal peptidase is an enzyme responsible for cleaving the signal peptide during protein translocation across the endoplasmic reticulum membrane. It is not directly involved in halting translation.
c. Stop-transfer peptide is a signal sequence within the polypeptide chain that causes the protein to remain embedded in the membrane during translation. However, it is not involved in transcription, so this option is incorrect.
d. Stop-transfer sequence is the correct term for the signal sequence that causes the protein to stop being translocated across the membrane during translation, and it therefore remains embedded. This consensus sequence is found on the inchoate (new) polypeptide.
e. The given option is the same as option d, so it is a duplicate option. There is no need for it to appear twice.
Based on the analysis, the correct answer is d. "Stop-transfer sequence, translation."